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Terminal oxidases belonging to oxygen, nitrate, sulfate, and sulfur respiratory pathways have been sequenced in members of both bacteria and archaea including cytochrome oxidase, nitrate reductase, adenylylsulfate reductase, sulfite reductase, and polysulfide reductase which can likewise be assigned to LUCA (Castresana & Moreira 1999).
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A specfic model of the evolution of the ribosome envisages that the smaller subunit which binds to and moves along the m RNA began first as an RNA-based RNA helicase which was essential to avoid the RNA era ending in non-replicating double stranded hairpins (Zenkin 2012).
This review will cover all these aspects, from the first life on Earth to Homo sapiens.
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